Houston at Milwaukee 1:10 PM ET
The road-weary Houston Astros will turn to left-hander Framber Valdez as they try to salvage the final game of the three-game series against the host Milwaukee Brewers on Wednesday.
Pittsburgh at St. Louis 1:15 PM ET
Coming off his first loss and worst outing of the season, veteran right-hander Sonny Gray will try to keep the St. Louis Cardinals' recent roll going when they host the Pittsburgh Pirates on Wednesday afternoon.
San Francisco at Chi. Cubs 2:20 PM ET
The San Francisco Giants have every reason to smile when left-hander Robbie Ray trots onto the field.
Seattle at Athletics 3:35 PM ET
Bryan Woo has dominated the Athletics no matter which city the franchise calls home.
NY Mets at Arizona 3:40 PM ET
Zac Gallen pitched the Arizona Diamondbacks to within one game of a second consecutive series victory over the New York Mets with a 5-1 win Tuesday. Each team will send out a quality arm in an attempt to secure the series finale Wednesday afternoon.
LA Dodgers at Miami 4:40 PM ET
It is a well-known fact that the Miami Marlins have the lowest payroll in the major leagues.
Texas at Boston 6:45 PM ET
After evening the three-game series on a night that featured clutch hitting from both Wilyer Abreu and Alex Bregman, the Boston Red Sox look for their second consecutive win over the visiting Texas Rangers in a Thursday matinee.
Texas at Boston 6:45 PM ET
The Boston Red Sox will enter Wednesday's game against the visiting Texas Rangers playing like a team in need of a jolt, but don't expect to see any type of shake up that includes Rafael Devers playing first base.
Philadelphia at Tampa Bay 7:05 PM ET
The Tampa Bay Rays are hoping to have their hottest hitter back in the lineup when they host the Philadelphia Phillies on Wednesday in the second contest of their three-game series.
San Diego at NY Yankees 7:05 PM ET
During a recent run of close defeats, the New York Yankees were pleased with the quality of their at-bats and felt a big inning was coming.
Cincinnati at Atlanta 7:15 PM ET
The Cincinnati Reds will send ace Hunter Greene to the mound on Wednesday, tasking him with trying to try end a four-game losing streak when they meet the Atlanta Braves on the road.
Baltimore at Minnesota 7:40 PM ET
just in time for the return of two of their most important contributors.
Chi. White Sox at Kansas City 7:40 PM ET
The Kansas City Royals have struggled to provide much run support for veteran Michael Wacha this season.
Detroit at Colorado 8:40 PM ET
The Colorado Rockies and Detroit Tigers had a scheduled day off before starting their three-game series in Denver on Tuesday. Heavy rain turned it into a two-day break.
Toronto at LA Angels 9:38 PM ET
Los Angeles Angels left fielder Taylor Ward has struggled to find the same results he achieved at the plate last season, leading him to spend considerable time in the batting cage before the team's home game against the Toronto Blue Jays on Tuesday in Anaheim, Calif.