Toronto at NY Yankees 1:05 PM ET
If there is a save situation, who gets the chance for the New York Yankees will be a big storyline.
Toronto at NY Yankees 1:05 PM ET
While Max Fried's first month with the New York Yankees is going well, Devin Williams is experiencing a rough time in his initial weeks for his new team.
Baltimore at Detroit 1:10 PM ET
The Detroit Tigers got an extra day of rest on Friday.
LA Angels at Minnesota 2:10 PM ET
Injuries continue to hit the infield of the Minnesota Twins, who will play the middle game of their three-game series against the Los Angeles Angels on Saturday afternoon in Minneapolis.
Milwaukee at St. Louis 2:15 PM ET
After losing six of seven games on their last road trip, the St. Louis Cardinals are trying to regain their footing at home.
Cincinnati at Colorado 3:10 PM ET
The Cincinnati Reds have a stable of young pitchers in their rotation, and after Andrew Abbott started the series opener, it's 25-year-old Hunter Greene's turn against the Colorado Rockies on Saturday afternoon in Denver.
NY Mets at Washington 4:05 PM ET
The Washington Nationals will look to pick up where they left off against the visiting New York Mets when the teams meet Saturday for the second contest of their four-game series.
Philadelphia at Chi. Cubs 4:05 PM ET
Philadelphia Phillies left-hander Jesus Luzardo hopes to continue impressing his new team when he takes the mound against the host Chicago Cubs in the second game of their three-game series on Saturday.
Texas at San Francisco 4:05 PM ET
The San Francisco Giants will host a big family reunion on Saturday that will feature their game against the Texas Rangers.
Chi. White Sox at Athletics 4:05 PM ET
The Athletics will try to climb above the .500 mark for the first time since the opening weekend of the season when they host the Chicago White Sox on Saturday afternoon in West Sacramento, Calif.
Boston at Cleveland 6:10 PM ET
Following a successful series against the leaders of the American League East, the Cleveland Guardians will take aim at the other storied franchise in that division.
Houston at Kansas City 7:10 PM ET
Two veteran starters who have gotten off to sluggish starts this season are set to take the mound Saturday night when the Kansas City Royals host the Houston Astros for the second game in their weekend series.
Atlanta at Arizona 8:10 PM ET
The Atlanta Braves continues to build on their strong recent homestead, buoyed by left-hander Chris Sale's first victory of the season Friday.
Tampa Bay at San Diego 8:40 PM ET
One of the Tampa Bay Rays' offensive mainstays for the past six years has started to hit.
Pittsburgh at LA Dodgers 9:10 PM ET
Shohei Ohtani will take another crack at recovering from his current downturn when the Los Angeles Dodgers play host to the Pittsburgh Pirates on Saturday in the middle contest of a three-game series.
Miami at Seattle 9:40 PM ET
The legend of Agustin Ramirez continues to grow.