SEATTLE -- Toronto first baseman Chris Colabello loves to be at the plate in clutch situations and he had delivered before in a big moment at Safeco Field.

So when the Seattle Mariners intentionally walked teammate Edwin Encarnacion to load the bases on Saturday in the top of the ninth inning, Colabello was ready. And he produced again with a tiebreaking, two-run single to lead the Blue Jays to an 8-6 win.

"My whole life, I've been that guy who wanted to drive in the runs in a big situation," said Colabello, whose first career home run came in the 13th inning of a 2013 win at Seattle. "I'm comfortable in that situation, for whatever reason. I certainly feel a little different when runners are in scoring position; I'm just one of those guys."

Colabello's bases-loaded single off Seattle closer Carson Smith in the top of the ninth capped a Toronto comeback from three runs down.

"He has gotten huge hits for us all year," Blue Jays manager John Gibbons said. "He puts the ball in play, and that was a perfect situation."

The Blue Jays (50-49) trailed 6-4 in the eighth before pinch-hitter Ezequiel Carrera tied the score with a two-run homer.

Toronto pitcher Aaron Sanchez, in his first relief appearance of the season after coming off the disabled list earlier in the day, got the win. Sanchez (6-4) pitched a scoreless eighth before Roberto Osuna came on to post his fifth save of the season with a scoreless ninth.

Smith (1-3) suffered the loss after coming in with the score tied in the top of the ninth. Former closer Fernando Rodney suffered his fifth blown save of the season when he served up Carrera's homer in the eighth.

"It has not been good as of late," Mariners manager Lloyd McClendon said of Rodney's recent struggles. "They've been tough losses."

Seattle (45-53) used home runs from second baseman Robinson Cano and backup catcher Jesus Sucre to rally from a 3-1 deficit in the top of the second.

Toronto starter Drew Hutchison, who was battling the flu, struggled through four innings while allowing seven hits and six runs (five earned). Hutchison served up homers to Cano and Sucre, the first of Sucre's career.

Hutchison refused to use his recent health battles as an excuse.

"You're expected to execute and do your job, and I wasn't able to do that," Hutchison said.

Former Blue Jays pitcher J.A. Happ couldn't even get through two innings in his first start against his former team. Four walks in the second inning, including two with the bases loaded, led to his departure after just 1 2/3 innings.

"We came in with a bullpen that was stressed," McClendon said, "and now we've got to cover 7 1/3 innings. That's tough."

After Seattle left fielder Seth Smith had given the Mariners a 1-0 lead on a sacrifice fly in the bottom of the first, Toronto scored three runs against a wild Happ in the top of the second. Left fielder Danny Valencia tied the score with an RBI single before two bases-loaded walks gave Toronto a 3-1 lead and ended Happ's outing after just 52 pitches.

Happ threw 43 pitches in the second inning and gave up three runs, one hit and four walks in 1 2/3 innings -- the southpaw's shortest outing in more than a year.

Seattle got one of the runs back on a solo home run from Sucre, who ended an 0-for-16 streak with the first homer of his career to pull the Mariners to 3-2 in the bottom of the second.

An error on Toronto second baseman Devon Travis put Cano on base in the third, leading to an unearned run as Cano came around to score on Logan Morrison's fielder's choice.

The Mariners scored in each of the first four innings, with the big blow a three-run homer from Cano in the fourth. His 10th home run of the season broke a tie to give Seattle a 6-3 lead.

Toronto got one run back on an RBI double from shortstop Jose Reyes in the sixth. Carrera's pinch-homer tied the score 6-6 two innings later, extending Toronto's streak of games with at least one home run to eight.

"It feels great knowing I just tied the game in the eighth inning," Carrera said of his homer.

Seattle's Smith walked the leadoff batter in the top of the ninth, then right fielder Jose Bautista's double put runners on second and third before the Mariners' closer intentionally walked designated hitter Edwin Encarnacion to get to Colabello.

Colabello, who hit his first career homer as a Minnesota Twin at Seattle on July 27, 2013, lined a single up the middle to score two runs on the way to the Toronto win.

"This is my favorite place besides (Toronto's) Rogers Centre to play," Colabello said. "I really like the city and I really like the ballpark. Obviously, it's really memorable after my first home run."

NOTES: Toronto RHP Drew Hutchison had his scheduled starts the previous two days pushed back before finally taking the mound Saturday. The flu prevented Hutchison from being able to start Thursday or Friday. ... Seattle starter J.A. Happ spent the last three seasons with the Blue Jays. He was traded for OF Michael Saunders in the offseason. ... Because of the short turnaround, the Mariners gave SS Brad Miller and C Mike Zunino the day off while using RF Nelson Cruz as the designated hitter. ... Seattle went into Saturday's game in search of its first three-game winning streak since late in May.