OAKLAND, Calif. -- With four previous walk-off hits in his career, Oakland Athletics first baseman Ike Davis thought he had seen it all.

Turns out, he wasn't even close.

Davis' infield single with two outs in the 10th inning scored Josh Reddick from third base and survived a video replay Wednesday night, giving the A's a 4-3 victory over the Toronto Blue Jays.

The win came five innings after A's manager Bob Melvin was ejected from the game. Melvin nonetheless was credited with his 369th victory as the team's skipper, moving him into third place on the Oakland list.

"What can I say?" Melvin shrugged afterward. "Great win."

Reddick, a late-game replacement, set up Davis' heroics with an opposite-field double with one out in the 10th off the Blue Jays' sixth pitcher, right-hander Roberto Osuna (1-4).

Reddick took third on third baseman Brett Lawrie's infield out before Davis' grounder toward left field was stabbed by a diving Blue Jays shortstop Jose Reyes.

Reyes' throw to first was deemed a bit too late, a call that passed video-replay inspection in New York far after the A's celebrated on the field.

"I was not sure. You never know," Davis said of the replay verdict, which took 2 minutes, 45 seconds. "Especially that one. I saw it on replay, and I couldn't tell."

After initially mobbing Davis near the pitcher's mound and showering him with water, about a dozen members of the A's waited alongside the hero until the umpires took off their headsets and called the game over.

As if they practiced it, the A's then darted single-file into the dugout.

"I was out there thinking, 'If they turn this over, we're going to look like a bunch of idiots,'" Reddick said. "It felt like the longest replay we'd had all year."

Left fielder Danny Valencia, who earlier had hit his seventh home run of the season, could only stand with his Blue Jays teammates in front of their dugout, waiting for the decision.

"If (the umpire originally) would have called him out and they would have replayed it, I felt that they would have said he was out," he said of the inconclusive nature of the replay. "It was a good play, a bang-bang play. We've seen it all year: It's got to be pretty much cut and dry that it's the opposite for them to overturn it."

Right-hander Fernando Rodriguez (1-1), Oakland's fourth pitcher, got the win after pitching a perfect top of the 10th.

A's starter Sonny Gray was three outs away from becoming the American League's fifth 11-game winner before the Blue Jays rallied for a tying run in the top of the ninth inning against Oakland closer Tyler Clippard.

After allowing a double to Blue Jays second baseman Devon Travis and two walks to load the bases with no outs, Clippard struck out Toronto third baseman Josh Donaldson before issuing a game-tying walk to right fielder Jose Bautista.

Clippard then struck out Blue Jays designated hitter Edwin Encarnacion and got catcher Dioner Navarro to fly out, retaining the 3-3 tie.

"That's tough, because now you're in a no-win situation," Melvin said of Clippard's feat. "Getting back in the dugout in a tie game obviously allowed us to win."

The loss snapped a modest two-game winning streak for the Blue Jays.

Like his A's counterpart, Toronto manager John Gibbons felt the game was ultimately decided in the top of the ninth.

"We're sitting bases loaded with no outs, got the guys coming up that we want, and only plated one run on a walk," he said. "That's baseball. (Clippard) gutted it out."

Melvin was ejected during a two-run fifth inning that broke a 1-1 tie and gave the home team a lead it held until the top of the ninth. First baseman Stephen Vogt and right fielder Jake Smolinski had RBIs in the tiebreaking inning.

Gray gave up nine hits and two runs in seven innings. The hit total matched the most he gave up in a game since April 17.

Valencia's homer off Gray came in the seventh inning. The solo shot got the Blue Jays within 3-2.

Left-hander Felix Doubront couldn't finish Oakland's difference-making fifth inning. He left after 4 2/3 innings, having allowed three runs (two earned) on seven hits. He walked two and struck out one.

Vogt, center fielder Billy Burns and catcher Josh Phegley had two hits apiece for the A's, who were out-hit 12-11 by the Blue Jays.

Catcher Russell Martin had three singles for the Blue Jays (48-48), who retained second place in the AL East despite the loss. Valencia and Donaldson, playing his second game in Oakland following an offseason trade, added two hits apiece.

Melvin's ejection occurred after the first pitch thrown to Vogt in the fifth inning was called a strike by plate umpire Hunter Wendelstedt. Burns, who singled on the previous pitch, stole second on the play.

Melvin's complaint focused on Martin, who stepped into the right-handed-hitters' batter's box during Doubront's delivery as if he were expecting a pitchout. However, the ball was thrown over the plate.

Two pitches later, Vogt singled to center field to score Burns, giving the A's a 2-1 lead.

A sacrifice fly by Smolinski later in the inning increased the margin to 3-1.

NOTES: Blue Jays RHP Drew Hutchison was ill Wednesday, and was scratched from his scheduled start Thursday in the series finale. RHP R.A. Dickey will be pushed up a day to start the game. ... The Blue Jays assigned veteran RHP Joba Chamberlain and INF/OF Ty Kelly to Triple-A Buffalo. Chamberlain was signed as a free agent, and Kelly was claimed off waivers from the St. Louis Cardinals. ... Blue Jays manager John Gibbons announced that RHP Aaron Sanchez would make a second rehab relief appearance at Buffalo on Thursday, after which the club would consider reinstating him this weekend or when it returns home next week. ... The A's were a winner in the competitive balance lottery Wednesday, landing the second pick after the first round in the 2016 amateur draft. Only teams in the 10 smallest markets and/or with the 10 smallest revenues were eligible for extra picks.