ANAHEIM, Calif. -- Stephen Vogt's three-run home run in the third inning propelled the Oakland A's to a 6-3 win over the Los Angeles Angels Monday night at Angel Stadium.

Vogt launched an 0-2 pitch from Angels starter Matt Shoemaker into the seats beyond the fence in right-center field, putting the A's up for good. A's designated hitter Billy Butler added two hits for the A's.

For the Angels, the loss was their third in a row and dropped them three games under .500 (5-8) for the first time this season. The loss also left them 0-4 in home games this season, following a season in which they had the best home record in the majors at 52-29.

And it was an unusual performance for Shoemaker, who had won nine consecutive decisions going back to Aug. 9 of last season. Shoemaker (2-1) gave up five runs, seven hits and three walks in three-plus innings. He had given up as many as five runs in a game only once last season in 20 starts.

A's starter Kendall Graveman wasn't much better, giving up three runs (two earned), four hits and three walks in three-plus innings. Right-hander Dan Otero (1-1) pitched four scoreless innings of relief, allowing just one hit, to earn the victory. Tyler Clippard pitched the ninth and got his first save of the season.

The A's threatened to put up a big inning in the first against Shoemaker, loading the bases with one out on two walks and a long single by Butler.

Shoemaker, though, escaped cheaply enough, giving up only a sacrifice fly by first baseman Ike Davis as the A's took a 1-0 lead.

The Angels responded with two runs in their half of the first inning, getting singles by center fielder Mike Trout and first baseman Albert Pujols, setting up third baseman David Freese's two-out, two-run single for a 2-1 Angels advantage.

The A's regained the lead in the third inning, following a double by center fielder Sam Fuld, an infield single by left fielder Mark Canha and a three-run home run by Vogt for a 4-2 lead.

The Angels narrowed their deficit to 4-3 in the bottom of the third after Trout reached on an error, stole second, and scored on a single by Pujols. But in the top of the fourth, Shoemaker gave up a home run to shortstop Marcus Semien to lead off the inning. The A's led, 5-3, and Shoemaker was through for the night.

NOTES: Oakland INF/OF Ben Zobrist had an MRI exam on his left knee after injuring it sliding into second base Sunday against the Royals. The MRI showed no ligament damage but did indicate frayed cartilage. Zobrist, who was scheduled to have a cortisone shot in the knee Monday night, will be out of the lineup at least until Thursday, if not longer. ... Starting Monday, the Angels began a stretch of 24 consecutive days during which they will not leave California. During that time, they will have two homestands and a trip to Oakland and San Francisco. The Angels' next game outside the state will be May 15 in Baltimore. ... The A's pitching staff has recorded five shutouts, most in the majors. ... Angels RHP Huston Street has retired all 12 batters he's faced this season.