Hunter Renfroe went deep twice as part of a six-homer attack, Adrian Houser pitched six shutout innings and the Milwaukee Brewers opened a three-game home series against the rival Chicago Cubs with an 11-1 romp on Friday night.

The Brewers never trailed en route to their fourth straight win, with Jace Peterson belting his first homer of the year as part of a three-run second and Andrew McCutchen hitting his second in two days in the third.

The hosts broke the game open when Christian Yelich hit his second homer of the season and Renfroe the first of his two in a three-run fifth to create a 7-0 lead.

Renfroe's second homer, his fourth of the season, was a two-run shot that made it 9-1 in the seventh, and Willy Adames added another two-run blast, his fifth homer of the season, to cap the game's scoring in the eighth.

Milwaukee's six homers were its most in a game since the Brewers smacked seven in a 15-14 win over the Washington Nationals in 2019.

Renfroe finished with three RBIs.

The Peterson, McCutchen and Yelich homers all came off Cubs starter Kyle Hendricks (1-2), who was gone after 4 1/3 innings, pounded for six runs and seven hits. He walked two and struck out two.

Houser (2-2) limited the Cubs to two hits in his six innings. He walked three and struck out six.

Chicago's lone run came in the seventh on a wild pitch by the Brewers' third pitcher, Jandel Gustave.

Renfroe, Adames and Lorenzo Cain had two hits each for the Brewers, while Renfroe, Adames and Rowdy Tellez scored twice apiece.

Alfonso Rivas had two of Chicago's three hits. The Cubs were outhit 13-3.

The Cubs had taken two of three from the Brewers in a season-opening series in Chicago. The Cubs outscored the visitors 18-9 in those games.

--Field Level Media