Renato Nunez homered twice and drove in four runs and the host Baltimore Orioles used a six-run fourth inning to blow out the Cleveland Indians 13-0 on Saturday.

Anthony Santander and Chance Sisco also homered and Andrew Cashner pitched seven shutout innings for Baltimore, which walloped the Indians by a 13-0 score for the second straight day.

Baltimore was leading 1-0 in the bottom of the fourth when Santander pulled a pitch just inside the right-field foul pole and onto Eutaw Street for a solo home run to begin the frame. The next two batters both reached base, and after a sacrifice bunt, Jonathan Villar roped a two-RBI double to make the score 4-0.

Trey Mancini followed with a double of his own to score Villar, and Nunez capped the inning with a two-run homer that forced Cleveland right-hander Zach Plesac (3-3) out of the ball game.

In the fifth, Mancini knocked in two more runs on a single that just got past Indians second baseman Jason Kipnis, pushing the lead to 9-0.

One inning later, Sisco hit a two-run home run to advance the lead to double digits. In the bottom of the seventh, Nunez hit his second two-run home run of the game, this time off Mike Freeman, who started the game at third base.

Cashner (8-3) was projected to start the game for the Orioles, but about 20 minutes before the scheduled start time, he was scratched. But when the game started after a 66-minute rain delay, Cashner was on the mound.

The 10-year veteran had arguably his best outing of the season. The right-hander allowed only three hits and one walk while striking out six.

Kevin Plawecki had two hits for Cleveland, while Baltimore's Nunez had two walks and three runs scored in addition to his two home runs.

With the victory, Baltimore claimed their first series win since they took two of three from the Chicago White Sox in April. The Indians lost back-to-back games for the first time in June.

--Field Level Media