Phillies 6, Indians 2: Jonathan Pettibone remained unbeaten in five major-league starts while John Mayberry Jr. had three hits and three RBIs as host Philadelphia downed Cleveland.

Kevin Frandsen and Domonic Brown each homered for Philadelphia, which dropped its first two games against the Indians by a combined 20-2 score on April 30-May 1. Pettibone (3-0) allowed two runs and four hits over a career-high 6 2/3 innings, departing after yielding a pair of hard-hit groundouts in the seventh.

Scott Kazmir (2-2) was tagged for four runs on six hits over five-plus innings in his worst outing since his season debut, leaving the game after surrendering Brown’s solo blast to lead off the sixth.

Frandsen staked the Phillies to an early lead in the opening inning when he lifted Kazmir’s 1-2 slider over the fence in left and just out of the reach of left fielder Michael Brantley. Nick Swisher singled and Carlos Santana doubled to open the second for Cleveland, which pulled ahead two batters later on Brantley’s two-run single.

Mayberry gave the Phillies the lead for good in the fourth with a two-run double and drove in an insurance run in the eighth with a single after Brown belted his seventh homer, tying Chase Utley for the team lead. Mayberry stole second and scored three batters later on an RBI single from Freddy Galvis.

GAME NOTEBOOK: Pettibone, who improved to 2-0 with a 2.45 ERA in three career starts at Citizens Bank Park, has yet to allow more than three runs in a start. … Cleveland, which entered Tuesday with wins in 13 of its last 16 games, dropped consecutive games for the first time since losing three straight from April 24-28. … The Phillies won for the 14th time in 18 games when they score more than three runs.