Baltimore 29, Atlanta 7
Joe Flacco threw for 258 yards and two touchdowns as Baltimore cruised past visiting Atlanta for its fifth win in six games.
Washington 19, Tennessee 17
Kai Forbath kicked a career-high four field goals, including a 22-yarder as time expired, as host Washington snapped a four-game losing streak.
St. Louis 28, Seattle 26
Stedman Bailey returned a punt 90 yards for a touchdown as host St. Louis handed Seattle its second straight loss.
Jacksonville 24, Cleveland 6
Denard Robinson broke out for a career-high 127 rushing yards and scored his first touchdown as host Jacksonville snapped a nine-game losing streak extending to last season.
Indianapolis 27, Cincinnati 0
Andrew Luck threw for 344 yards and the Indianapolis defense dominated visiting Cincinnati in a battle of division leaders.
Buffalo 17, Minnesota 16
Kyle Orton found Sammy Watkins for a 2-yard touchdown with one second left as Buffalo edged visiting Minnesota.
Miami 27, Chicago 14
Ryan Tannehill threw for two touchdowns and Miami forced three turnovers to send Chicago to its worst start at home since 2004.
Detroit 24, New Orleans 23
Matthew Stafford threw two touchdown passes in the final 3:38 as host Detroit rallied from a 13-point, fourth-quarter deficit to stun New Orleans.
Green Bay 38, Carolina 17
Aaron Rodgers continued his MVP-caliber campaign by recording as many touchdown passes as incompletions in a crisp victory for host Green Bay.
Kansas City 23, San Diego 20
Cairo Santos kicked his third field goal, a 48-yarder with 21 seconds to play in the fourth quarter, as visiting Kansas City snapped San Diego's five-game winning streak.
Arizona 24, Oakland 13
Carson Palmer threw two touchdown passes and running back Stepfan Taylor finished with a pair of scores as visiting Arizona kept Oakland winless on the season.
Dallas 31, N.Y. Giants 21
Tony Romo threw for three touchdowns and DeMarco Murray set an NFL record by registering his seventh straight 100-yard performance to begin the season as host Dallas posted its sixth consecutive victory.
Denver 42, San Francisco 17
Peyton Manning shattered the NFL record for career scoring passes, throwing for 318 yards and four touchdowns as host Denver pummeled San Francisco.