No. 24 Oklahoma State 59, No. 25 Texas Tech 21: Clint Chelf threw three touchdowns to Isaiah Anderson in a lopsided first half and the Cowboys posted a fourth-straight win over the visiting Red Raiders.

Joseph Randle accounted for 91 of 256 rushing yards for Oklahoma State (7-3, 5-2 Big 12), which broke it open early with 28 straight points after Eric Stephens' 1-yard touchdown run tied the game at 7-7 at the start of the second quarter.

It was the fifth straight loss in Stillwater for Texas Tech (7-4, 4-4) and its second straight blowout loss in the series. Oklahoma State cruised to a 66-6 rout in Lubbock last season.

Chelf, who threw for four touchdowns last week against West Virginia, got the start despite Wes Lunt being fully recovered from a concussion. He had little problem throwing against what had been the 11th-best pass defense (172.3 yards) in the nation. Chelf hit Anderson for scores of 60, 33 and 66 yards - all in the second quarter - to stake the Cowboys to a 35-14 halftime advantage.

Anderson finished with four catches for 174 yards. Chelf was 11-of-21 for 229 yards, with all of the yardage coming in the first half while Texas Tech's Seth Doege was 24-of-36 for 230 yards with a touchdown and two interceptions.

GAME NOTEBOOK: With the game well in hand, Chelf threw only four passes in the second half. ... Oklahoma State had the ball for only 11:05 in the first half. ... Doege entered with an FBS-best 34 touchdown passes. ... Four players had at least 40 rushing yards for the Cowboys.