No. 16 Clemson 45, Boston College 31: Tajh Boyd threw for 367 yards and accounted for four touchdowns and DeAndre Hopkins caught 11 passes for a school-record 197 yards as the visiting Tigers rebounded from last week's loss to Florida State.

Chase Rettig passed for 341 yards and three touchdowns for Boston College (1-3, 0-2 ACC). Alex Amidon hauled in two of the scores and finished with 193 yards on eight receptions.

Clemson (4-1, 1-1) grabbed a 24-21 halftime edge after two see-saw quarters when Boyd hit Brandon Ford on a tight 4-yard pass just inside sideline with 23 seconds left in the half. Touchdown runs by Roderick McDowell and Andre Ellington pushed the margin to 38-21 with 3:07 remaining in the third.

After spotting the Eagles a 7-0 lead, the Tigers reeled off 17 unanswered points as Boyd ran for a 6-yard score and threw a 15-yard touchdown pass to Sam Cooper. Boyd's 35-yard touchdown toss to Hopkins early in the fourth brought the lead back to 17 at 45-28.

Andre Williams sparked Boston College's ground game – which entered ranked 114th – with a 30-yard scoring run less than five minutes into the game, but the Eagles managed only 21 rushing yards thereafter.

GAME NOTEBOOK: Clemson played without All-American WR Sammy Watkins, who sat out with an abdominal virus. Backup WR Martavis Bryant (groin) also missed the game. … Tigers K Chandler Catanzaro extended his school record of consecutive made field goals to 16 with a 28-yarder. … Boston College WR Bobby Swigert returned after missing the first three games with a knee injury and had two catches for 27 yards plus a 28-yard pass completion.