UCLA scored touchdowns on two of its first three plays from scrimmage and the Bruins hammered visiting Colorado 45-6 on Saturday.

UCLA became bowl-eligible and remains atop the Pac-12 South division. The Bruins can earn a spot in the inaugural conference championship game with a win against rival USC in their season finale.

Kevin Prince threw a career-best four touchdown passes and UCLA (6-5, 5-3 Pac-12) racked up 553 of total offense. Prince was 15-of-19 for 225 yards and connected with Shaquelle Evans on a 54-yard scoring pass on his first throw of the night.

Joseph Fauria caught two touchdown passes and Nelson Rosario had another. UCLA built a 21-0 lead and were never threatened. Johnathan Franklin gained 162 yards on 15 carries and scored a 14-yard touchdown.

Colorado, which won its first Pac-12 game last week, got a 20-yard touchdown pass from Tyler Hansen to Toney Clemons on the first play of the second quarter but the Buffaloes (2-10, 1-7) managed little else en route to their 24th straight loss outside the state of Colorado.